|
KMID : 1039420190530010062
|
|
Journal of Pathology and Translational Medicine
2019 Volume.53 No. 1 p.62 ~ p.65
|
|
|
TFE3-Expressing Perivascular Epithelioid Cell Tumor of the Breast
|
|
Kim Hyun-Jin
Kim Ji-Min
Lee Se-Kyung
Cho Eun-Yoon
Cho Soo-Youn
|
|
|
Abstract
|
|
|
|
Perivascular epithelioid cell tumor (PEComa) is a very rare mesenchymal tumor with a distinctive morphology and immunophenotype. PEComas usually harbor TSC2 alterations, although TFE3 translocations, which occur in MiT family translocation renal cell carcinoma and alveolar soft part sarcoma, are also possible. We recently experienced a case of PEComa with TFE3 expression arising in the breast. An 18-year-old female patient presented with a right breast mass. Histologically, the tumor consisted of epithelioid cells with alveolar structure and showed a diffuse strong expression of HMB45 and TFE3. TSC2 was preserved. Melan A and smooth muscle actin were negative. To our knowledge, this is the first Korean case of PEComa of the breast that intriguingly presented with TFE3 expression.
|
|
|
KEYWORD
|
|
|
Perivascular epithelioid cell neoplasms, TFE3, Breast
|
|
|
FullTexts / Linksout information
|
|
|
|
|
Listed journal information
|
|
  
|